Hypervalent iodine compounds: reagents of the future
نویسندگان
چکیده
منابع مشابه
Thioamination of Alkenes with Hypervalent Iodine Reagents
An efficient thioamination of alkenes mediated by iodine(III) reagents is described. The use of different sulfur nucleophiles allows the flexible synthesis of 1,2-aminothiols from alkenes. By employing chiral iodine(III) reagents, a stereoselective version of the thioamination protocol has also been developed.
متن کاملAsymmetric Synthesis with Hypervalent Iodine Reagents.
This chapter describes recent developments in stereoselective synthesis using hypervalent iodine reagents.
متن کاملStereoselective Ketone Rearrangements with Hypervalent Iodine Reagents.
The first stereoselective version of an iodine(III)-mediated rearrangement of arylketones in the presence of orthoesters is described. The reaction products, α-arylated esters, are very useful intermediates in the synthesis of bioactive compounds such as ibuprofen. With chiral lactic acid-based iodine(III) reagents product selectivities of up to 73 % ee have been achieved.
متن کاملFacile Oxidative Rearrangements Using Hypervalent Iodine Reagents
Aromatic substituents migrate in a novel oxidative cyclization mediated by iodine(III) reagents. 4-Arylbut-3-enoic acids are cyclized and rearranged to 4-arylfuran-2(5H)-ones by hypervalent iodine compounds in good to excellent yields under mild reaction conditions. Other ring sizes are also accessible. The mechanism of the reaction is described in detail, and calculations highlight the cationi...
متن کاملNovel Iodine Mediated Carbocyclisations and Hypervalent Iodine(iii) Reagents
The first chapter focuses on the introduction of iodine m ediated carbocyclisations and their applications continue to present a stim ulating challenge in targetand diversityoriented syntheses. Literature overview of m ore than past two decades about this area of research has been highlighted by including key examples along with the ir m echanistic aspects. The second chapter discusses applicat...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2020
ISSN: 1551-7012
DOI: 10.24820/ark.5550190.p011.145